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Proto-mapping the areas of cerebral cortex: transcription factors make the grade

Nature Neuroscience volume 3, pages 640–641 (2000)Cite this article

An Erratum to this article was published on 01 December 2000

Two new studies demonstrate how the homeodomain genes Emx2 and Pax6 may work together to provide positional information to the developing neocortex.

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Figure 1: Emx2 and Pax6 are expressed in opposing gradients across cortical progenitor cells, and their loss leads to distinctive shifts in the positions and sizes of cortical areas.

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Author notes

  1. Edwin S. Monuki and Christopher A. Walsh: Both authors are in the Department of Neurology, Beth Israel Deaconess Medical Center, Boston, Massachusetts , 02115, USA.

Authors and Affiliations

  1. Department of Pathology Division of Neuropathology, Children's Hospital, Boston, 02115, Massachusetts, USA

    Edwin S. Monuki

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  1. Edwin S. Monuki
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  2. Christopher A. Walsh
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Monuki, E., Walsh, C. Proto-mapping the areas of cerebral cortex: transcription factors make the grade. Nat Neurosci 3, 640–641 (2000). https://doi.org/10.1038/76587

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