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Pool rules

A study in this issue uses a new technique to show that synaptic vesicles released spontaneously and those released in response to action potentials are drawn from distinct, non-overlapping pools that coexist in presynaptic terminals.

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Figure 1: Evoked and spontaneous release in the presence of green and red fluorescent dyes, respectively, label distinct and non-overlapping pools of vesicles.

Katie Vicari

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Sullivan, J. Pool rules. Nat Neurosci 12, 671–673 (2009). https://doi.org/10.1038/nn0609-671

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