Abstract
By combining photoconversion of FM1-43-stained vesicles and electron microscopy of hippocampal synapses, we find evidence that the population of morphologically docked synaptic vesicles corresponds to the release-ready neurotransmitter quanta. Furthermore, those synaptic vesicles that are participating in cycles of exo- and endocytosis tend to be closer to the active zone than vesicles that are being held in reserve.
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Schikorski, T., Stevens, C. Morphological correlates of functionally defined synaptic vesicle populations. Nat Neurosci 4, 391–395 (2001). https://doi.org/10.1038/86042
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DOI: https://doi.org/10.1038/86042
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