Cold emerging from the fog

Proposed mechanisms for the sensation of cold have focused on single proteins. A paper in this issue reports that cold trans-duction depends on a complex interplay among ion channels.

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Figure 1: Multiple ion channels contribute to cold-induced firing of action potentials in cold-sensitive neurons and pharmacologically modified cold-insensitive neurons.

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MacDermott, A., Lee, C. Cold emerging from the fog. Nat Neurosci 5, 189–190 (2002). https://doi.org/10.1038/nn0302-189

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