Abstract
In a rat model of cocaine craving, a new study shows that activation of the protein kinase ERK in the amygdala is necessary and sufficient for the growth of craving over time in withdrawal. The combination of experimental approaches used by these authors will serve as a model for future studies examining the molecular mechanisms underlying a cognitive or behavioral process.
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Carrasquillo, Y., Sweatt, J. Craving cocaine pERKs up the amygdala. Nat Neurosci 8, 129–130 (2005). https://doi.org/10.1038/nn0205-129
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DOI: https://doi.org/10.1038/nn0205-129
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