A study shows that selective lesions of the orbital prefrontal cortex in macaques spare behavioral flexibility and emotional processing but impair a test of outcome expectation, suggesting that some psychiatric disorders ascribed to a disrupted orbital prefrontal cortex may instead be caused by more widespread dysfunction.
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Baxter, M., Croxson, P. Behavioral control by the orbital prefrontal cortex: reversal of fortune. Nat Neurosci 16, 984–985 (2013). https://doi.org/10.1038/nn.3472
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DOI: https://doi.org/10.1038/nn.3472