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Behavioral control by the orbital prefrontal cortex: reversal of fortune

Nature Neuroscience volume 16, pages 984985 (2013) | Download Citation

A study shows that selective lesions of the orbital prefrontal cortex in macaques spare behavioral flexibility and emotional processing but impair a test of outcome expectation, suggesting that some psychiatric disorders ascribed to a disrupted orbital prefrontal cortex may instead be caused by more widespread dysfunction.

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Affiliations

  1. Mark G. Baxter and Paula L. Croxson are in the Glickenhaus Laboratory of Neuropsychology, Department of Neuroscience and Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA.

    • Mark G Baxter
    •  & Paula L Croxson

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Competing interests

The authors declare no competing financial interests.

Corresponding author

Correspondence to Mark G Baxter.

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DOI

https://doi.org/10.1038/nn.3472

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