In a case of sex-linked epigenetic inheritance, paternal cocaine use results in a heritable increase in cortical Bdnf gene expression that confers a cocaine-resistant phenotype in male, but not female, progeny.
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Mapping the past, present and future research landscape of paternal effects
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Scofield, M., Kalivas, P. Forgiving the sins of the fathers. Nat Neurosci 16, 4–5 (2013). https://doi.org/10.1038/nn.3288
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DOI: https://doi.org/10.1038/nn.3288
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