How do we feel temperature? A study now finds that a recently discovered anion channel is a temperature sensor that, like previously identified cation channels, mediates the perception of noxious hot temperatures.
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References
Dhaka, A., Viswanath, V. & Patapoutian, A. Annu. Rev. Neurosci. 29, 135–161 (2006).
Basbaum, A.I., Bautista, D.M., Scherrer, G. & Julius, D. Cell 139, 267–284 (2009).
Cho, H. et al. Nat. Neurosci. 15, 1015–1021 (2012).
Noël, J. et al. EMBO J. 28, 1308–1318 (2009).
Caterina, M.J. et al. Science 288, 306–313 (2000).
Park, U. et al. J. Neurosci. 31, 11425–11436 (2011).
Lee, H., Iida, T., Mizuno, A., Suzuki, M. & Caterina, M.J. J. Neurosci. 25, 1304–1310 (2005).
Miyamoto, T., Petrus, M.J., Dubin, A.E. & Patapoutian, A. Nat. Commun. 2, 369 (2011).
Vriens, J. et al. Neuron 70, 482–494 (2011).
Schroeder, B.C., Cheng, T., Jan, Y.N. & Jan, L.Y. Cell 134, 1019–1029 (2008).
Yang, Y.D. et al. Nature 455, 1210–1215 (2008).
Caputo, A. et al. Science 322, 590–594 (2008).
Nieto-Posadas, A., Jara-Oseguera, A. & Rosenbaum, T. Curr. Top. Med. Chem. 11, 2131–2150 (2011).
Patapoutian, A., Tate, S. & Woolf, C.J. Nat. Rev. Drug Discov. 8, 55–68 (2009).
Xiao, B., Coste, B., Mathur, J. & Patapoutian, A. Nat. Chem. Biol. 7, 351–358 (2011).
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Bandell, M., Patapoutian, A. A hot new channel. Nat Neurosci 15, 931–933 (2012). https://doi.org/10.1038/nn.3148
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DOI: https://doi.org/10.1038/nn.3148
