Stimulus-evoked neural activity is attenuated on stimulus repetition (repetition suppression), a phenomenon that is attributed to largely automatic processes in sensory neurons. By manipulating the likelihood of stimulus repetition, we found that repetition suppression in the human brain was reduced when stimulus repetitions were improbable (and thus, unexpected). Our data suggest that repetition suppression reflects a relative reduction in top-down perceptual 'prediction error' when processing an expected, compared with an unexpected, stimulus.
Subscribe to Journal
Get full journal access for 1 year
only $18.75 per issue
All prices are NET prices.
VAT will be added later in the checkout.
Rent or Buy article
Get time limited or full article access on ReadCube.
All prices are NET prices.
Grill-Spector, K., Henson, R. & Martin, A. Trends Cogn. Sci. 10, 14–23 (2006).
Henson, R.N. Prog. Neurobiol. 70, 53–81 (2003).
Miller, E.K., Li, L. & Desimone, R. Science 254, 1377–1379 (1991).
Wiggs, C.L. & Martin, A. Curr. Opin. Neurobiol. 8, 227–233 (1998).
Grill-Spector, K. & Malach, R. Acta Psychol. (Amst.) 107, 293–321 (2001).
Kourtzi, Z. & Kanwisher, N. Science 293, 1506–1509 (2001).
Desimone, R. Proc. Natl. Acad. Sci. USA 93, 13494–13499 (1996).
Friston, K. Phil. Trans. R. Soc. Lond. B 360, 815–836 (2005).
Henson, R., Shallice, T. & Dolan, R. Science 287, 1269–1272 (2000).
Kanwisher, N., McDermott, J. & Chun, M.M. J. Neurosci. 17, 4302–4311 (1997).
Murray, S.O. & Wojciulik, E. Nat. Neurosci. 7, 70–74 (2004).
Friston, K., Kilner, J. & Harrison, L. J. Physiol. (Paris) 100, 70–87 (2006).
Bar, M. & Aminoff, E. Neuron 38, 347–358 (2003).
Kersten, D., Mamassian, P. & Yuille, A. Annu. Rev. Psychol. 55, 271–304 (2004).
Summerfield, C. & Koechlin, E. Neuron published online, doi: 10.1016/j.neuron.2008.05.21 (2008).
We are grateful to E. Koechlin and S. Kouider for helpful comments on an earlier version of this manuscript. This work was supported in part by a grant from the US National Institute of Neurological Disorders and Stroke (NS30863, M.-M.M.).
About this article
Cite this article
Summerfield, C., Trittschuh, E., Monti, J. et al. Neural repetition suppression reflects fulfilled perceptual expectations. Nat Neurosci 11, 1004–1006 (2008) doi:10.1038/nn.2163
Consciousness and Cognition (2020)
Decoding the neural representation of self and person knowledge with multivariate pattern analysis and data-driven approaches
Wiley Interdisciplinary Reviews: Cognitive Science (2019)
Temporal expectations modulate face image repetition suppression of early stimulus evoked event-related potentials
The Keio Journal of Medicine (2019)