News & Views | Published:

RNA dynamics revealed by metabolic RNA labeling and biochemical nucleoside conversions

Nature Methods volume 15, pages 171172 (2018) | Download Citation

The combination of metabolic RNA labeling with biochemical nucleoside conversion now adds a broadly applicable temporal dimension to RNA sequencing.

Access optionsAccess options

Rent or Buy article

Get time limited or full article access on ReadCube.

from$8.99

All prices are NET prices.

References

  1. 1.

    et al. Nat. Methods 14, 1198–1204 (2017).

  2. 2.

    , , , & Nat. Methods 15, 221–225 (2018).

  3. 3.

    et al. Angew. Chem. Int. Edn. Engl. 56, 13479–13483 (2017).

  4. 4.

    et al. RNA 14, 1959–1972 (2008).

  5. 5.

    , , & Nat. Methods 6, 439–441 (2009).

  6. 6.

    et al. Mol. Syst. Biol. 7, 458 (2011).

  7. 7.

    et al. Genome Res. 22, 2031–2042 (2012).

  8. 8.

    et al. Science 352, 1225–1228 (2016).

  9. 9.

    et al. Genes Dev. 27, 98–115 (2013).

Download references

Author information

Affiliations

  1. Marisa A.P. Baptista and Lars Dölken are at the Institute of Virology and Immunobiology, Julius Maximilian University of Würzburg, Würzburg, Germany.

    • Marisa A P Baptista
    •  & Lars Dölken

Authors

  1. Search for Marisa A P Baptista in:

  2. Search for Lars Dölken in:

Competing interests

The authors declare no competing financial interests.

Corresponding author

Correspondence to Lars Dölken.

About this article

Publication history

Published

DOI

https://doi.org/10.1038/nmeth.4608

Newsletter Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing