Small chemical tweaks during tissue preparation make a big difference for imaging thick, complex biological samples.
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Pallotto, M. et al. Extracellular space preservation aids the connectomic analysis of neural circuits. eLife doi:10.7554/eLife.08206 (9 December 2015).
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de Souza, N. Simple tools for difficult imaging. Nat Methods 13, 112–113 (2016). https://doi.org/10.1038/nmeth.3756
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DOI: https://doi.org/10.1038/nmeth.3756