KinomeXplorer: an integrated platform for kinome biology studies

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Figure 1: Overview of the improved NetworKIN algorithm in KinomeXplorer.

References

  1. 1

    Seet, B.T., Dikic, I., Zhou, M.M. & Pawson, T. Nat. Rev. Mol. Cell Biol. 7, 473–483 (2006).

  2. 2

    Lim, W.A. & Pawson, T. Cell 142, 661–667 (2010).

  3. 3

    Davis, M.I. et al. Nat. Biotechnol. 29, 1046–1051 (2011).

  4. 4

    Anastassiadis, T., Deacon, S.W., Devarajan, K., Ma, H. & Peterson, J.R. Nat. Biotechnol. 29, 1039–1045 (2011).

  5. 5

    Dinkel, H. et al. Nucleic Acids Res. 39, D261–D267 (2011).

  6. 6

    Linding, R. et al. Cell 129, 1415–1426 (2007).

  7. 7

    Janes, K.A. et al. Science 310, 1646–1653 (2005).

  8. 8

    Yaffe, M.B. Sci. Signal. 6, pe13 (2013).

  9. 9

    Miller, M.L. et al. Sci. Signal. 1, ra2 (2008).

  10. 10

    Gough, N.R. Sci. Signal. 6, eg3 (2013).

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Acknowledgements

We would like to thank members of R.L.'s laboratory for useful input on the manuscript, and A. Pasculescu for input on the data collection. This work was supported by the Lundbeck Foundation, the Human Frontier Science Program (HFSP), the Danish Council for Independent Research (FSS) and the European Research Council (ERC).

Author information

Correspondence to Lars Juhl Jensen or Rune Linding.

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Competing interests

The authors declare no competing financial interests.

Supplementary information

Supplementary Text and Figures

Supplementary Figures 1 and 2, and Supplementary Note (PDF 757 kb)

Supplementary Table 1

Benchmark of the NetworKIN method (XLS 44 kb)

Supplementary Table 2

Dataset for training NetPhorest and NetworKIN (XLS 3640 kb)

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Horn, H., Schoof, E., Kim, J. et al. KinomeXplorer: an integrated platform for kinome biology studies. Nat Methods 11, 603–604 (2014). https://doi.org/10.1038/nmeth.2968

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