KinomeXplorer: an integrated platform for kinome biology studies

Access options

Rent or Buy article

Get time limited or full article access on ReadCube.

from$8.99

All prices are NET prices.

Figure 1: Overview of the improved NetworKIN algorithm in KinomeXplorer.

References

  1. 1

    Seet, B.T., Dikic, I., Zhou, M.M. & Pawson, T. Nat. Rev. Mol. Cell Biol. 7, 473–483 (2006).

    CAS  Article  Google Scholar 

  2. 2

    Lim, W.A. & Pawson, T. Cell 142, 661–667 (2010).

    CAS  Article  Google Scholar 

  3. 3

    Davis, M.I. et al. Nat. Biotechnol. 29, 1046–1051 (2011).

    CAS  Article  Google Scholar 

  4. 4

    Anastassiadis, T., Deacon, S.W., Devarajan, K., Ma, H. & Peterson, J.R. Nat. Biotechnol. 29, 1039–1045 (2011).

    CAS  Article  Google Scholar 

  5. 5

    Dinkel, H. et al. Nucleic Acids Res. 39, D261–D267 (2011).

    CAS  Article  Google Scholar 

  6. 6

    Linding, R. et al. Cell 129, 1415–1426 (2007).

    CAS  Article  Google Scholar 

  7. 7

    Janes, K.A. et al. Science 310, 1646–1653 (2005).

    CAS  Article  Google Scholar 

  8. 8

    Yaffe, M.B. Sci. Signal. 6, pe13 (2013).

    PubMed  Google Scholar 

  9. 9

    Miller, M.L. et al. Sci. Signal. 1, ra2 (2008).

    Article  Google Scholar 

  10. 10

    Gough, N.R. Sci. Signal. 6, eg3 (2013).

    PubMed  Google Scholar 

Download references

Acknowledgements

We would like to thank members of R.L.'s laboratory for useful input on the manuscript, and A. Pasculescu for input on the data collection. This work was supported by the Lundbeck Foundation, the Human Frontier Science Program (HFSP), the Danish Council for Independent Research (FSS) and the European Research Council (ERC).

Author information

Affiliations

Authors

Corresponding authors

Correspondence to Lars Juhl Jensen or Rune Linding.

Ethics declarations

Competing interests

The authors declare no competing financial interests.

Supplementary information

Supplementary Text and Figures

Supplementary Figures 1 and 2, and Supplementary Note (PDF 757 kb)

Supplementary Table 1

Benchmark of the NetworKIN method (XLS 44 kb)

Supplementary Table 2

Dataset for training NetPhorest and NetworKIN (XLS 3640 kb)

Rights and permissions

Reprints and Permissions

About this article

Verify currency and authenticity via CrossMark

Cite this article

Horn, H., Schoof, E., Kim, J. et al. KinomeXplorer: an integrated platform for kinome biology studies. Nat Methods 11, 603–604 (2014). https://doi.org/10.1038/nmeth.2968

Download citation

Further reading