Abstract
Tremendous controversy has surrounded efforts to undertake research on totipotent human stem cells. To date public policy in the United States has attempted to skirt the ethical and social questions raised by this research. Annas et al. argue that research using human embryos as a source of totipotent stem cells can secure broad public support if there is an open and public discussion about the ethical justification for undertaking such research and the assurance of adequate federal regulation and oversight.
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References
Thomson, J.A. et al. Embryonic stem cell lines derived from human blastocysts. Science 282, 1145–1147 (1998).
2. Shamblott, M.J. et al. Derivation of pluripotent stem cells from cultured human primordial germ cells. Proc. Natl. Acad. Sci. USA 95, 13726–13731 (1998).
Annas, G.J. & Elias, S. The politics of transplantation of human fetal tissue. N. Engl. J. Med. 320, 1079–1082 (1989).
Office of the Director, National Institutes of Health, Fact Sheet: Stem Cell Research, January 19, 1999 (2 pp).
Caplan, A. & Garry, D.L. Are there really alternatives to the use of fetal tissue from elective abortions in transplantation research? N. Engl. J. Med. 322, 1592–1596 (1992).
Public Law 105–277, sec. 511 (1998).
Annas, G.J., Caplan, A. & Elias, S.E. The politics of human-embryo research–avoiding ethical gridlock. N. Engl. J. Med. 1996; 334: 1329–32.
National Bioethics Advisory Commission. Ethical Issues in Stem Cell Research, Final Report. US G.P.O., September 1999.
Feiler, C.L. Human embryo experimentation: regulation and relative rights. Fordham Law Rev. 66, 2435–2465 (1998).
Lanza, R.P., Cibelli, J.B. & West, M.D. Human therapeutic cloning. Nature Med. 5, 975–977 (1999).
Massachusetts General Law code 112, sec. 12J.
Geron Ethics Advisory Board. Research on Human Embryonic Stem Cells: Ethical Considerations 1–14 (Geron Corporation, Menlo Park, California, December 1998).
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Annas, G., Caplan, A. & Elias, S. Stem cell politics, ethics and medical progress. Nat Med 5, 1339–1341 (1999). https://doi.org/10.1038/70900
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DOI: https://doi.org/10.1038/70900