Human and animal research suggests Crohn's disease is a heterogeneous group of disorders and implicates commensal bacteria in genetically determined mucosal T-cell dysregulation.
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Targan, S., Karp Murphy, L. Clarifying the causes of Crohn's. Nat Med 1, 1241–1243 (1995). https://doi.org/10.1038/nm1295-1241
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