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Quelling cholesterol pathway fends off brain damage

Nature Medicine volume 15, pages 13581359 (2009) | Download Citation

Subjects

A molecular pathway known for regulating cholesterol and lipid metabolism is now implicated in stroke (pages 1399–1406). The pathway is bumped up by N-methyl-D-aspartate glutamate receptors (NMDARs), which are hyperactivated in stroke and other conditions.

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Author information

Affiliations

  1. Maria T. Bengoechea-Alonso and Johan Ericsson are at the School of Medicine and Medical Science Conway Institute, University College Dublin, Belfield, Dublin, Ireland.

    • Maria T Bengoechea-Alonso
    •  & Johan Ericsson

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Correspondence to Johan Ericsson.

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DOI

https://doi.org/10.1038/nm1209-1358

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