News & Views | Published:

Breaking the pain connection

Nature Medicine volume 14, pages 13131315 (2008) | Download Citation

Subjects

A small peptide eases pain in several types of mouse models. The peptide targets a protein interaction within a pain-mediating complex—containing the N-methyl-D-aspartate receptor—without affecting normal physiological processes (pages 1325–1332).

Access optionsAccess options

Rent or Buy article

Get time limited or full article access on ReadCube.

from$8.99

All prices are NET prices.

References

  1. 1.

    , , , & Ann. NY Acad. Sci. 1088, 164–186 (2006).

  2. 2.

    & Science 288, 1765–1768 (2000).

  3. 3.

    & J. Med. Chem. 50, 2557–2562 (2007).

  4. 4.

    et al. Nat. Med. 14, 1325–1332 [(2008).

  5. 5.

    , , , & Nat. Neurosci. 3, 661–669 (2000).

  6. 6.

    & Nat. Rev. Neurosci. 5, 317–328 (2004).

  7. 7.

    et al. Proc. Natl. Acad. Sci. USA 101, 6237–6242 (2004).

  8. 8.

    , , & Trends Neurosci. 26, 696–705 (2003).

  9. 9.

    , & Mol. Ther. 16, 1776–1782 (2008).

  10. 10.

    et al. Eur. J. Neurosci. 22, 1445–1454 (2005).

  11. 11.

    et al. Curr. Biol. 13, 321–328 (2003).

  12. 12.

    & Nat. Neurosci. 10, 1361–1368 (2007).

Download references

Author information

Affiliations

  1. Catherine J. Pallen is in the Department of Pediatrics and the Child & Family Research Institute, University of British Columbia, 950 West Twenty-Eighth Avenue, Vancouver, British Columbia V5Z 4H4, Canada.  cpallen@interchange.ubc.ca

    • Catherine J Pallen

Authors

  1. Search for Catherine J Pallen in:

About this article

Publication history

Published

DOI

https://doi.org/10.1038/nm1208-1313

Further reading

Newsletter Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing