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Marrow to muscle, fission versus fusion

Bone marrow cells can reconstitute muscle, but which cells contribute to the process, and how do they do it? Two studies trace the journey of a single hematopoietic stem cell into muscle tissue (pages 1520–1527 and 1528–1532).

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Figure 1: Different mechanisms by which transplanted stem cells potentially participate in regenerative myogenesis.

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Rudnicki, M. Marrow to muscle, fission versus fusion. Nat Med 9, 1461–1462 (2003). https://doi.org/10.1038/nm1203-1461

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