A new technique identifies Salmonella genes that are preferentially expressed during infection of host cells.
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References
Valdivia, R.H. & Falkow, S. Fluorescence-based isolation of bacterial genes expressed within host Cells. Science 277, 2007–2011 (1997).
Cormack, B.P., Valdivia, R.H. & Falkow, S. FACS-optimized mutants of the green fluorescent protein (GFP). Gene 173, 33–38 (1996).
Mahan, M.J. et al. Antibiotic-based selection for bacterial genes that are specifically induced during infection of a host. Proc. Natl. Acad. Sci. USA 92, 669–673 (1995).
Heithoff, D.M. et al. Bacterial infection as assessed by in vivo gene expression. Proc. Natl. Acad. Sci. USA 94, 934–939 (1997).
García Véscovi, E., Soncini, F.C. & Groisman, E.A. Mg2+ as an extracellular signal: Environmental regulation of Salmonella virulence. Cell 84, 165–174 (1996).
Rathman, M., Sjaastad, M.D. & Falkow, S. Acidification of phagosomes containing Salmonella typhimurium in murine macrophages. Infect. Immun. 64, 2765–2773 (1996).
Valdivia, R.H. & Falkow, S. Bacterial genetics by flow cytometry: Rapid isolation of Salmonella typhimurium acid-inducible promoters by differential fluorescence induction. Mol. Microbiol. 22, 367–378 (1996).
Groisman, E.A. & Ochman, H. How Salmonella became a pathogen. Trends Microbiol. 5, 343–349 (1997).
Abshire, K.Z. & Neidhardt, F.C. Growth rate paradox of Salmonella typhimurium within host macrophages. J. Bacteriol. 175, 3744–3748 (1993).
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Groisman, E. A green light for virulence gene expression. Nat Med 3, 1190–1191 (1997). https://doi.org/10.1038/nm1197-1190
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DOI: https://doi.org/10.1038/nm1197-1190