“Sometimes, it's like the patent discussion has degraded into a third-grade name-calling contest... 'na, na, na, you're a troll,'” says Daniel Ravicher, executive director of the not-for-profit legal advisory organization the Public Patent Foundation, an organization that most likely has never been compared to this type of mythical creature.

What many call 'patent trolls' are most properly referred to as nonproducing entities, or NPEs. They're typically defined as companies or individuals that horde patents not for actual use, but simply as tools to squeeze other companies for lawsuit settlements and licensing fees. They operate within the law and yet pose a big problem for high-tech industries. Legal actions can take successful technologies off the market and drain money that often would be otherwise devoted to research and development. However, thus far, NPE-type activities have been relatively absent in the pharmaceutical industry—though some predict this could change.

“We need to look honestly at these perfectly legal companies, because they're an element of a patent system that is becoming more and more abused,” says Ravicher.

Pejoratively, the simplest abstract example of an NPE would be a group of lawyers with a bank account and catalog of patents, explains Chris Reohr, cofounder of Patent Freedom, a company that tracks NPEs. The most commonly cited case of what's typically referred to as NPE litigation, however, is the 2006 US Supreme Court case eBay, Inc. v. MercExchange, LLC, in which the latter had an extensive catalog of unused patents that described web-based tools for online auctions, including one that covered eBay's 'Buy-it-Now' function. The case set a legal precedent for how courts should deal with NPE-type companies. What's more, it implemented a set of rules that had the result of limiting NPEs' bargaining power. Nevertheless, such activity continues to grow.

According to Patent Freedom's estimates, the percentage of patent lawsuits involving NPEs has risen from just 2% in 1998 to 13% in 2008. The jump has even been cited by the Obama administration as a need for patent reform. However, the boom has been almost entirely within high-tech industries involving computer hardware and software. Patent Freedom's system of charting litigation has yet to pick up on any litigation specifically relating to pharmaceuticals.

Matthew Rimmer, a senior lecturer at the Australian National University in Canberra and author of Intellectual Property and Biotechnology, says that NPEs are much more troublesome in the field of information technology (IT), because an individual IT product tends to have many components that would require many patents. So, it's easy for an NPE to have one vague patent that may cover one aspect of another entity's device or software. Pharmaceuticals, in contrast, tend to deal with products that have one patent for one arduously researched chemical. Further protection of pharmaceuticals in the US is provided by the country's issuance of data exclusivity by the Food and Drug Administration and by regulation of generic drugs.

Stanford University law professor Mark Lemley adds that, although no one would call them NPEs, university-associated institutions sometimes have an NPE-like role in the pharmaceutical industry by aggressively enforcing patents they hold. For example, in a 2006 working paper (Stanford Public Law Working Paper No. 980776), he cites the Wisconsin Alumni Research Foundation's rigorous enforcement of stem-cell patents, among others.

The pharmaceutical industry almost always comes down on the side of patent law that strengthens patent enforcement (and, thus, the ability of NPEs to practice). However, Rimmer says that even the pharmaceutical industry may not be able maintain its NPE immunity for very long.

“It's not the definition of an NPE that counts. It's the larger problem that patents are becoming less about actually protecting innovation and more about exploitation,” Rachiver says. “Don't count on that changing any time soon.”