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Bad chaperone

Defects in microtubules are associated with a number of human diseases. Now, a chaperone protein that helps create microtubules is pinpointed in an inherited disorder.

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Figure 1: Tubulin chaperones.

Kimberly Homer

Figure 2: Individuals with Kenney-Caffey syndrome have cells with abnormal tubulin architecture.

Parvari et al. , Nature Genetics

References

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Lewis, S., Cowan, N. Bad chaperone. Nat Med 8, 1202–1203 (2002). https://doi.org/10.1038/nm1102-1202

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  • DOI: https://doi.org/10.1038/nm1102-1202

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