Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

Dietary salt and blood pressure

High salt intake is believed to have adverse effects on blood pressure levels in humans. Now, for the first time, it has been shown to increase blood pressure in chimpanzees (pages 1009–1016).

This is a preview of subscription content, access via your institution

Relevant articles

Open Access articles citing this article.

Access options

Buy article

Get time limited or full article access on ReadCube.

$32.00

All prices are NET prices.

References

  1. Ruskin, A. Classics in Arterial Hypertension (Thomas, Springfield, Illinois, 1956).

    Google Scholar 

  2. Stamler, J. Dietary salt and blood pressure. in The Third International Conference on Nutrition in Cardiovascular Diseases (eds Lee, K.T., Oike, Y. & Kanazawa, T.) Ann. N.Y. Acad. Sci. 676, 122–156. (1993).

    Google Scholar 

  3. Stamler, J., Stamler, R. & Pullman, T. (eds) The Epidemiology of Hypertension. (Grune & Stratton, New York, 1967).

    Google Scholar 

  4. Cutler, J.A., Kotchen, T.A. & Obarzanek, E. (guest eds) The National Heart, Lung, and Blood Institute Workshop on Salt and Blood Pressure. Hypertension 17 (Suppl. I), I-1–I-221 (1991).

    Google Scholar 

  5. McKeown, T. The direction of medical research. Lancet ii, 1281–1284. (1979).

    Article  Google Scholar 

  6. Denton, D. et al. The effect of increase of salt intake on blood pressure of chimpanzees. Nature Med. 1, 1009–1016. (1995).

    CAS  Article  Google Scholar 

  7. INTERSALT Cooperative Research Group. INTERSALT: An international study of electrolyte excretion and blood pressure: Results for 24 hour urinary sodium and potassium excretion. Br. Med. J. 297, 319–328. (1988).

  8. Dyer, A.R., Elliott, P., Shipley, M., Stamler, R. & Stamler, J. for the INTERSALT Cooperative Research Group. Body mass index and associations of sodium and potassium with blood pressure in INTERSALT. Hypertension 23, 729–736. (1994).

    CAS  Article  Google Scholar 

  9. Neaton, J.D., Kuller, L., Stamler, J. & Wentworth, D.N. Impact of systolic and diastolic blood pressure on cardiovascular mortality. in Hypertension: Physiology, Diagnosis, and Management, 2nd ed. (eds Laragh, J.H. & Brenner, B.M.) 127–144. (Raven Press, New York, 1995).

    Google Scholar 

  10. Rose, G. The Strategy of Preventive Medicine. (Oxford Medical Publications, Oxford, 1992).

    Google Scholar 

  11. Burt, V.L. et al. Prevalence of hypertension in the US adult population Results from the Third National Health and Nutrition Examination Survey 1988–91. Hypertension 25, 305–313. (1995).

    CAS  Article  Google Scholar 

  12. National High Blood pressure Education program. The fifth report of the Joint National Committee on Detection, Evaluation, and Treatment of High Blood Pressure (JNC V). Arch. intern. Med. 153, 154–183. (1993).

  13. National High Blood pressure Education program. National High Blood Pressure Education Program Working Group report on primary prevention of hypertension. Arch. intern. Med. 153, 186–208. (1993).

  14. Shaper, A.G. Communities without hypertension. in Cardiovascular Disease in the Tropics 1:40 PMs Shaper, A. G., Hutt, M.S.R. & Fejfar, Z.) 77–83. (British Medical Association, London, 1974).

    Google Scholar 

  15. Page, L.B., Damon, A. & Moellering, R.C. Antecedents of cardiovascular disease in six Solomon Island Societies. Circulation 49, 1132–1146. (1974).

    CAS  Article  Google Scholar 

  16. Law, M.R., Frost, C.D. & Wald, N.J. By how much does dietary salt reduction lower blood pressure? I - Analysis of observational data among populations. II - Analysis of observational data within populations. III - Analysis of data from trials of salt reduction. Br. Med. J. 302, 811–824. (1991).

    CAS  Article  Google Scholar 

  17. Weinberger, M. Sodium and volume sensitivity of blood pressure: Age and pressure change over time. Hypertension 18, 67–71. (1991).

    CAS  Article  Google Scholar 

  18. Cardiovascular Review Group, Committee on Medical Aspects of Food Policy. Report on Nutritional Aspects of Cardiovascular Disease (Department of Health, Report on Health and Social Policy Number 46, Her Majesty's Stationery Office, London, 1974).

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and Permissions

About this article

Cite this article

Dyer, A., Stamler, R., Elliott, P. et al. Dietary salt and blood pressure. Nat Med 1, 994–996 (1995). https://doi.org/10.1038/nm1095-994

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/nm1095-994

Further reading

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing