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HIV: The more things change, the more they stay the same

Nature Medicine volume 1, pages 991–993 (1995)Cite this article

New data on the AIDS virus suggest that an HIV-1 subtype, ‘clade’ E, which is prevalent in Asia, may spread easily through mucosa, accounting for the greater efficiency of heterosexual spread of the disease in that part of the world.

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References

  1. Saag, M.S. et al. Extensive variation of human immunodeficiency virus type 1 in vitro. Nature 334, 440–444. (1988).

    Article  CAS  PubMed  Google Scholar 

  2. Travers, K. et al. Natural protection against HIV-1 infection provided by HIV-2. Science 268, 1612–1615. (1995).

    Article  CAS  PubMed  Google Scholar 

  3. Kunanusont, C. et al. HIV-1 subtypes and male-to-female transmission in Thailand. Lancet 345, 1078–1083. (1995).

    Article  CAS  PubMed  Google Scholar 

  4. Jacquez, J.A., Koopman, J.S., Simon, C.P. & Longini, Jr., I.M. Role of the primary infection in epidemics of HIV infection in gay cohorts. J. Acquired Immun. Defic. Syndr. 7, 1169–1184. (1994).

    CAS  Google Scholar 

  5. Machado, A.A. et al. Neutralizing antibodies against highly cytopathic Zairian human immunodeficiency type-1 virus (HIV-1) NDK are present in sera outside Africa. Vaccine 13, 321–325. (1995).

    Article  CAS  PubMed  Google Scholar 

  6. Couto-Fernandez, J.C. et al. Genetic and antigenic variability of HIV type 1 in Brazil. AIDS Research and Human Retroviruses 10, 1157–1163. (1994).

    Article  CAS  PubMed  Google Scholar 

  7. Sabino, E.C. et al. Identification of human immunodeficiency virus type 1 envelope genes recombinant between subtypes B and F in two epidemiologically linked individuals from Brazil. J. Virol 68, 6340–6346. (1994).

    CAS  PubMed  PubMed Central  Google Scholar 

  8. Diaz, R. et al. Dual human immunodeficiency virus type 1 infection and recombination in a dually exposed transfusion recipient. J. Virol. 69, 3273–3281. (1995).

    CAS  PubMed  PubMed Central  Google Scholar 

  9. Louwagie, J. et al. Genetic diversity of the envelope glycoprotein from human immunodeficiency virus type 1 isolates of African origin. J. Virol. 69, 263–271. (1995).

    CAS  PubMed  PubMed Central  Google Scholar 

  10. Artenstein, A. et al. Dual infection with human immunodeficiency virus type 1 of distinct envelope subtypes in humans. J. Inf. Dis. 171, 805–810. (1995).

    Article  CAS  Google Scholar 

Download references

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  1. School of Public Health, The University of Michigan, Ann Arbor, Michigan, 48109, USA

    June E. Osborn

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  1. June E. Osborn
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Osborn, J. HIV: The more things change, the more they stay the same. Nat Med 1, 991–993 (1995). https://doi.org/10.1038/nm1095-991

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