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Merging mitochondria for neuronal survival

Loss of mitochondrial fusion causes a rapid degeneration of cerebellar Purkinje cells.

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Figure 1: Mitochondrial abnormalities in degenerating Mfn2-deficient Purkinje cells.

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Manfredi, G., Beal, M. Merging mitochondria for neuronal survival. Nat Med 13, 1140–1141 (2007). https://doi.org/10.1038/nm1007-1140

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