Thrombin leads to blood clotting through activation of specialized G protein–coupled receptors. In mice, small peptides call pepducins inhibit thrombin receptors and prevent blood clotting (pages 1161–1165).
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Bahou, W. Attacked from within, blood thins. Nat Med 8, 1082–1083 (2002). https://doi.org/10.1038/nm1002-1082
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DOI: https://doi.org/10.1038/nm1002-1082
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