The complexity of factors that regulate bleeding and coagulation has long confounded researchers. Andrew Wei and Shaun Jackson help clear the air by examining clinical findings pointing to a mechanistic basis for a common bleeding disorder, immune thrombocytopenic purpura. Mark Kahn tackles two research studies that could lead to improved therapies for a coagulation syndrome that hits people with severe sepsis.
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Kahn, M. Counteracting clotting in sepsis. Nat Med 14, 918–919 (2008). https://doi.org/10.1038/nm0908-918
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DOI: https://doi.org/10.1038/nm0908-918