A population of neurons in patients with familial amyotrophic lateral sclerosis have multiple abnormalities, including protein aggregation and mitochondrial dysfunction. Two studies now reveal interactions between these two defects.
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Dawson, V. Maiming mitochondria in familial ALS. Nat Med 10, 905–906 (2004). https://doi.org/10.1038/nm0904-905
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DOI: https://doi.org/10.1038/nm0904-905