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When good cholesterol goes bad

High density lipoprotein (HDL) is often called the 'good cholesterol.' Products of an inflammatory enzyme, myeloperoxidase, are now shown to selectively target the main protein in HDL, apolipoprotein A-I. This turns the 'good cholesterol' bad.

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Figure 1: Converting the HDL from anti-inflammatory to proinflammatory.

Michael Pace

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Fogelman, A. When good cholesterol goes bad. Nat Med 10, 902–903 (2004). https://doi.org/10.1038/nm0904-902

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  • DOI: https://doi.org/10.1038/nm0904-902

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