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Suppressing a sick heart

Nature Medicine volume 11, pages 828–829 (2005)Cite this article

A snarl of regulators influence cardiac hypertrophy, but factors that negatively regulate this process are not well understood. A new molecule has now emerged that seems to control pathologic but not physiologic cardiac hypertrophy in mice. It works by repressing the activity of a key transcription factor after both molecules are induced (pages 837–844).

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Figure 1: NAB1 negatively regulates pathologic cardiac hypertrophy.

Ann Thomson

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Authors and Affiliations

  1. Department of Pathology, and Department of Haematology, Centre for Vascular Research, University of New South Wales, The Prince of Wales Hospital, Sydney, Australia

    Levon M Khachigian

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  1. Levon M Khachigian
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Khachigian, L. Suppressing a sick heart. Nat Med 11, 828–829 (2005). https://doi.org/10.1038/nm0805-828

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