Before leaving the body, cholesterol is converted to bile acids. Two studies implicate the nuclear receptor SHP as a major player in bile-acid production—but not the only one.
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References
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Schoonjans, K., Auwerx, J. A sharper image of SHP. Nat Med 8, 789–791 (2002). https://doi.org/10.1038/nm0802-789
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DOI: https://doi.org/10.1038/nm0802-789
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