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A mouse model for hepatitis C virus infection?

Patients with hepatitis C constitute the highest proportion of candidates for liver transplantation. The lack of small animal models for the disease has been a major stumbling block in understanding how hepatitis C and liver damage develop and in testing possible treatments. The report of infection of a mouse model with the hepatitis C virus is a significant and welcome achievement. (pages 927–933)

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Figure 1: Schematic representation of the procedure for achieving hepatitis C virus infection in mice.

Bob Crimi

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Fausto, N. A mouse model for hepatitis C virus infection?. Nat Med 7, 890–891 (2001). https://doi.org/10.1038/90917

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