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Cystic fibrosis salt/fluid controversy: In the thick of it

A new study shows that a mouse model of cystic fibrosis has lower levels of liquid on the surface of its airway epithelium which suggests that thickened airway secretions might have a role in the disease process and that rehydrating the airways might be of benefit to patients.

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Figure 1: Defective mucociliary clearance in the CF: will hydration therapy correct it?

Renee Lucas

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Guggino, W. Cystic fibrosis salt/fluid controversy: In the thick of it. Nat Med 7, 888–889 (2001). https://doi.org/10.1038/90914

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