The road to effective vaccines based on DNA sequences may soon be more easily travelled (pages 583–587).
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References
Wolff, J.A. et al. Direct gene transfer into mouse muscle in vivo. Science 247, 1465–1468 (1990).
Williams, R.S. et al. Introduction of foreign genes into tissues of living mice by DNA coated microprojectiles. Proc. natn. Acad. Sci. U.S.A. 88, 2726–2730 (1991).
Tang, D.C., Devit, M. & Johnston, S.A. Genetic immunization is a simple method for eliciting an immune response. Nature 356, 152–154 (1992).
Ulmer, J.B. et al. Heterologous protection against influenza by injection of DNA encoding a viral protein. Science 259, 1745–1749 (1992).
Ulmer, J.B. et al. Protective immunity by intramuscular inection of low doses of influenza virus DNA vaccines. Vaccine 12: 1541–1544 (1994).
Donnelly, J.J. et al. Preclinical efficacy of a prototype DNA vaccine: Enhanced protection against antigenic drift in influenza virus. Nature Med. 1, xxx–xxx (1995).
Webster, R.G., Fynan, E.F., Santoro, J.C. & Robinson, H. Protection of ferrets against influenza challenge with a DNA vaccine to the haemagglutinin. Vaccine 12, 1495–1498 (1994).
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Krishnan, S., Haensler, J. & Meulien, P. Paving the way towards DNA vaccines. Nat Med 1, 521–522 (1995). https://doi.org/10.1038/nm0695-521
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DOI: https://doi.org/10.1038/nm0695-521
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