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  • Between Bedside and Bench
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Sudden Cardio Arrest: When normal ECG variants turn lethal

Nature Medicine volume 16, pages 646–647 (2010)Cite this article

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Numerous factors can contribute to sudden cardiac death, from underlying disease after myocardial infarction to genetic variants that can claim young lives. In 'Bedside to Bench', Stanley Nattel examines recent clinical studies suggesting that a particular type of readout on an electrocardiogram (ECG) may increase the risk of the condition. This ECG 'variant' is relatively common and was previously thought to be benign. In 'Bench to Bedside', Gordon Tomaselli and Andreas Barth take a look at studies at the bench examining how oxidative stress may promote sudden cardiac death.

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Figure 1: Mechanisms of early repolarization, and other associated conditions.

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Authors and Affiliations

  1. Stanley Nattel is in the Department of Medicine and Research Center, and the Department of Pharmacology and Therapeutics, Montreal Heart Institute and Université de Montréal, McGill University, Montreal, Quebec, Canada.,

    Stanley Nattel

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  1. Stanley Nattel
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Correspondence to Stanley Nattel.

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The author declares no competing financial interests.

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Nattel, S. Sudden Cardio Arrest: When normal ECG variants turn lethal. Nat Med 16, 646–647 (2010). https://doi.org/10.1038/nm0610-646

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