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IFN-α wakes up sleeping hematopoietic stem cells

Nature Medicine volume 15, pages 612–613 (2009)Cite this article

The cytokine interferon-α stimulates the turnover and proliferation of hematopoietic cells in vivo (pages 696–700). The findings hint at a new strategy to treat hematopoietic cancers.

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Figure 1: Role of low-level and induced IFNα signaling within HSCs.

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Authors and Affiliations

  1. Department of Medicine, Division of Hematology/Oncology, Emmanuelle Passegué is at the Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California–San Francisco, San Francisco, California, USA,

    Emmanuelle Passegué

  2. Department of Genetics and Norris Cotton Cancer Center, Patricia Ernst is at the Dartmouth Medical School, Hanover, New Hampshire, USA. Passeguee@stemcell.ucsf.edu or patricia.ernst@dartmouth.edu,

    Patricia Ernst

Authors
  1. Emmanuelle Passegué
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  2. Patricia Ernst
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Passegué, E., Ernst, P. IFN-α wakes up sleeping hematopoietic stem cells. Nat Med 15, 612–613 (2009). https://doi.org/10.1038/nm0609-612

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