Two articles in this issue highlight mechanisms that improve the immune system's on-site responsiveness and demonstrate how non-specific factors contribute to specific immunity in transplant settings. (pages 575–581 & 582–587)
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Kirk, A. Location, location, location: Regional immune mechanisms critically influence rejection. Nat Med 8, 553–555 (2002). https://doi.org/10.1038/nm0602-553
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DOI: https://doi.org/10.1038/nm0602-553
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