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References
Solimena, M. & De Camilli, P. Coxsackieviruses and diabetes. Nature Med. 1, 25–26 (1995).
Jones, D.B. & Armstrong, N.W. Coxsackie virus and diabetes revisited. Nature Med. 1, 284 (1995).
Baekkeskov, S. et al. Identification of the 64K autoantigen in insulin-dependent diabetes as the GABA synthesizing enzyme glutamic acid decarboxylase. Nature 347, 151–156, (1990).
Castano, L., Russo, E., Zhou, L., Lipes, M.A. & Eisenbarth, G.S. Identification and cloning of a granule autoantigen (carboxypeptidase H) associated with type 1 diabetes. J. clin. Endocrinol. Metab. 73, 1197–1201 (1991).
Baum, H., Butler, P., Davies, H., Sternberg, M. & Burroughs, A. Autoimmune disease and molecular mimicry: an hypothesis. Trends biochem. Sci. 18, 140–144 (1993).
Chicz, R.M. et al. Specificity and promiscuity among naturally processed peptides bound to HLA-DR alleles. J. exp. Med. 178, 27–47 (1993).
Baum, H. & Cunningham, P. Do MHC antigens generate pathogenetic peptides? Immun. Today 15, 388–389 (1994).
Gearon, C.L., Peakman, M., Vergani, D. & Baum, H. Mimicry between an islet autoantigen and MHC class II molecules as a mechanism of autoimmune diabetes. Diabetic Med. (in the press).
Todd, J.A. Genetic control of autoimmunity in type 1 diabetes. Immun. Today 11, 122–128 (1990).
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Baum, H., Brusic, V., Choudhuri, K. et al. MHC molecular mimicry in diabetes. Nat Med 1, 388 (1995). https://doi.org/10.1038/nm0595-388
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DOI: https://doi.org/10.1038/nm0595-388
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