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Neurons tame T cells

Multiple sclerosis occurs when T cells attack myelin in the central nervous system. Experiments in a mouse model of the disease suggest that neurons fight back by inducing regulatory T cells that dampen the immune response (pages 518–525).

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Figure 1: Neurons talking.

Katie Ris

References

  1. Liu, Y. et al. Nat. Med. 12, 518–525 (2006).

    Article  CAS  Google Scholar 

  2. Kumar, V. J. Clin. Invest. 114, 1222–1226 (2004).

    Article  CAS  Google Scholar 

  3. Racke, M.K. et al. J. Neuroimmunol. 107, 205–215 (2000).

    Article  CAS  Google Scholar 

  4. Kieseier, B.C., Hemmer, B. & Hartung, H.P. Curr. Opin. Neurol. 18, 211–220 (2005).

    Article  CAS  Google Scholar 

  5. Hafler, D.A. et al. Immunol. Rev. 204, 208–231 (2005).

    Article  CAS  Google Scholar 

  6. Swierkosz, J.E. & Swanborg, R.H. J. Immunol. 115, 631–633 (1975).

    CAS  PubMed  Google Scholar 

  7. Flügel, A. et al. Brain Pathol. 10, 353–364 (2000).

    Article  Google Scholar 

  8. Neumann, H. et al. Science 269, 549–552 (1995).

    Article  CAS  Google Scholar 

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Fujinami, R. Neurons tame T cells. Nat Med 12, 503–504 (2006). https://doi.org/10.1038/nm0506-503

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