Some commonly used pain medications inhibit the production of amyloid-β, a toxic peptide thought to have a major role in Alzheimer disease. New studies suggest that some COX-2 inhibitors may do the opposite—promote the production of this toxic peptide (pages 545–550).
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Katherine Ris
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Wyss-Coray, T. Killing pain, killing neurons?. Nat Med 11, 472–473 (2005). https://doi.org/10.1038/nm0505-472
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DOI: https://doi.org/10.1038/nm0505-472
