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Cisplatin and the sensitive cell

Epigenetic suppression of FANCF, a member of the Fanconi anemia gene family, is now implicated in some ovarian cancers. Might this suppression explain the sensitivity of such cancers to the cross-linking agent cisplatin (pages 568–574)?

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Figure 1: Damage control.

Kimberly Homer

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Bagby, G., Olson, S. Cisplatin and the sensitive cell. Nat Med 9, 513–514 (2003). https://doi.org/10.1038/nm0503-513

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