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Choosing between GVHD and delayed engraftment

Growth factors used to accelerate engraftment after hematopoietic cell transplantation can increase the severity of graft-versus-host disease. Experiments with mice examine how irradiation, used to prepare recipients for transplants, contributes to this problem (pages 436–441).

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Figure 1: Transplantation's balancing act.

Kim Caesar

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Martin, P. Choosing between GVHD and delayed engraftment. Nat Med 15, 363–364 (2009). https://doi.org/10.1038/nm0409-363

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