Only one drug is widely used to treat schistosomiasis, a chronic, neglected tropical disease caused by parasitic blood flukes. Fears of potential drug resistance have accelerated the search for new classes of antischistosome drugs. A promising candidate has now emerged (pages 407–412).
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References
King, C.H., Dickman, K. & Tisch, D.J. Lancet 365, 1561–1569 (2005).
Finkelstein, J.L., Schleinitz, M.D., Carabin, H. & McGarvey, S.T. PLoS Negl. Trop. Dis. 2, e158 (2008).
Sayed, A.A. et al. Nat. Med. 14, 407–412 (2008).
World Health Organization. WHO Model List of Essential Medicines, 15th edn., 1–27 (World Health Organization, Geneva, 2007).
Fenwick, A. Science 313, 1077–1081 (2006).
Fallon, P.G. & Doenhoff, M.J. Am. J. Trop. Med. Hyg. 51, 83–88 (1994).
Inglese, J. et al. Proc. Natl. Acad. Sci. USA 103, 11473–11478 (2006).
Alger, H.M. & Williams, D.L. Mol. Biochem. Parasitol. 121, 129–139 (2002).
Simeonov, A. et al. PLoS Negl. Trop. Dis. 2, e127 (2008).
van der Werf, M.J. et al. Acta Trop. 86, 125–139 (2003).
Croft, S.L. Trans. R. Soc. Trop. Med. Hyg. 99 Suppl 1, S9–S14 (2005).
McManus, D.P. & Loukas, A. Clin. Microbiol. Rev. 21, 225–242 (2008).
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Loukas, A., Bethony, J. New drugs for an ancient parasite. Nat Med 14, 365–367 (2008). https://doi.org/10.1038/nm0408-365
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DOI: https://doi.org/10.1038/nm0408-365
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