The streptococcal toxic shock syndrome causes a massive leak of plasma from the circulation, leading to low blood pressure and respiratory failure. Now this leakage is traced to the effects of neutrophils activated by a bacterial surface protein.
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Cohen, J. Shock factor shed by microbe. Nat Med 10, 342–343 (2004). https://doi.org/10.1038/nm0404-342
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DOI: https://doi.org/10.1038/nm0404-342