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Shock factor shed by microbe

The streptococcal toxic shock syndrome causes a massive leak of plasma from the circulation, leading to low blood pressure and respiratory failure. Now this leakage is traced to the effects of neutrophils activated by a bacterial surface protein.

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Figure 1: Bacterial M protein induces shock.

Kimberly Caesar

Figure 2: Scanning electron micrograph of normal lung tissue.

Reprinted with permission of Cell Press

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Cohen, J. Shock factor shed by microbe. Nat Med 10, 342–343 (2004). https://doi.org/10.1038/nm0404-342

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