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References
Cech, T.R. Ribozymes and their medical implications. JAMA 260, 3030–3034 (1988).
Symons, R.H. Small catalytic RNAs. Annu. Rev. Biochem. 61, 641–671 (1992).
Kashani-Sabet, M. et al. Reversal of the malignant phenotype by an anti-ras ribozyme. Antisense Res. Dev. 2, 3–15 (1992).
Baltimore, D. Intracellular immunization. Nature 325, 395–396 (1988).
Yu, M., Poeschla, E. & Wong-Staal, F. Progress towards gene therapy for HIV infection. Gene Therapy 1, 13–26 (1994).
Lee, S.-W., Gallardo, H.F., Gilboa, E. & Smith, C. Inhibition of human immunodeficiency virus type 1 in human T cells by a potent Rev response element decoy consisting of the 13-nucleotide minimal Revbinding domain. Virology 68, 8254–8264 (1994).
Terns, M.P., Dahlberg, J.E. & Lund, E. Multiple cis-acting signals for export of pre-U1 snRNA from the nucleus. Genes Dev. 7, 1898–1908 (1993).
Sullenger, B.A. & Cech, T.R. Tethering ribozymes to a retroviral packaging signal for destruction of viral RNA. Science 262, 1566–1569 (1993).
Sullenger, B.A. & Cech, T.R. Ribozyme-mediated repair of defective mRNA by targeted trans-splicing. Nature 371, 619–622 (1994).
Beaudry, A.A. & Joyce, G.F. Directed evolution of an RNA enzyme. Science 257, 635–641 (1992).
Bartel, D.P. & Szostak, J.W. Isolation of new ribozymes from a large pool of random sequences. Science 261, 1411–1418 (1993).
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Thompson, J., Macejak, D., Couture, L. et al. Ribozymes in gene therapy. Nat Med 1, 277–278 (1995). https://doi.org/10.1038/nm0395-277
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DOI: https://doi.org/10.1038/nm0395-277
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