Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

A close look at cancer

Advances in cancer research are enabling fast-paced discovery and translation of results into potential clinical tools. Here we consider some of the most influential findings of the past two years, selected by experts in the cancer field.

This is a preview of subscription content, access via your institution

Relevant articles

Open Access articles citing this article.

Access options

Buy article

Get time limited or full article access on ReadCube.

$32.00

All prices are NET prices.

Figure 1: Notable advances in cancer research.

References

  1. Quintana, E. et al. Nature 456, 593–598 (2008).

    Google Scholar 

  2. Parsons, D.W. et al. Science 321, 1807–1812 (2008).

    Google Scholar 

  3. Cancer Genome Atlas Research Network. Nature 455, 1061–1068 (2008).

  4. Jones, S. et al. Science 321, 1801–1806 (2008).

    Google Scholar 

  5. Mardis, E.R. et al. N. Engl. J. Med. 361, 1058–1066 (2009).

    Google Scholar 

  6. Mossé, Y.P. et al. Nature 455, 930–935 (2008).

    Google Scholar 

  7. Wood, L.D. et al. Science 318, 1108–1113 (2007).

    Google Scholar 

  8. Pleasance, E.D. et al. Nature 463, 184–190 (2010).

    Google Scholar 

  9. Mullighan, C.G. et al. Science 322, 1377–1380 (2008).

    Google Scholar 

  10. Yan, H. et al. N. Engl. J. Med. 360, 765–773 (2009).

    Google Scholar 

  11. Dang, L. et al. Nature 462, 739–744 (2009).

    Google Scholar 

  12. Ward, P.S. et al. Cancer Cell 17, 225–234 (2010).

    Google Scholar 

  13. Lapidot, T. et al. Nature 367, 645–648 (1994).

    Google Scholar 

  14. Kelly, P.N. et al. Science 317, 337 (2007).

    Google Scholar 

  15. Mani, S.A. et al. Cell 133, 704–715 (2008).

    Google Scholar 

  16. Rosen, J.M. & Jordan, C.T. Science 324, 1670–1673 (2009).

    Google Scholar 

  17. Al-Hajj, M. et al. Proc. Natl. Acad. Sci. USA 100, 3983–3988 (2003).

    Google Scholar 

  18. Barker, N. et al. Nature 457, 608–611 (2009).

    Google Scholar 

  19. Goldstein, A.S. et al. Science 329, 568–571 (2010).

    Google Scholar 

  20. Poulikakos, P.I. et al. Nature 464, 427–430 (2010).

    Google Scholar 

  21. Hatzivassiliou, G. et al. Nature 464, 431–435 (2010).

    Google Scholar 

  22. Heidorn, S.J. et al. Cell 140, 209–221 (2010).

    Google Scholar 

  23. Edwards, S.L. et al. Nature 451, 1111–1115 (2008).

    Google Scholar 

  24. Sakai, W. et al. Nature 451, 1116–1120 (2008).

    Google Scholar 

  25. Fong, P.C. et al. N. Engl. J. Med. 361, 123–134 (2009).

    Google Scholar 

  26. Sharma, S.V. et al. Cell 141, 69–80 (2010).

    Google Scholar 

  27. Weber, J.S. et al. J. Clin. Oncol. 26, 5950–5956 (2008).

    Google Scholar 

  28. DeNardo, D.G. et al. Cancer Cell 16, 91–102 (2009).

    Google Scholar 

  29. Andreu, P. et al. Cancer Cell 17, 121–134 (2010).

    Google Scholar 

Download references

Acknowledgements

We thank all of our survey respondents for their seminal insights into the recent advances in cancer research and the authors of the Book Reviews, News & Views, Timeline, Perspectives and Reviews for their crucial contributions to this Focus on Cancer.

Author information

Authors and Affiliations

Authors

Ethics declarations

Competing interests

The author declares no competing financial interests.

Rights and permissions

Reprints and Permissions

About this article

Cite this article

Farrell, A. A close look at cancer. Nat Med 17, 262–265 (2011). https://doi.org/10.1038/nm0311-262

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/nm0311-262

Further reading

Search

Quick links

Nature Briefing: Cancer

Sign up for the Nature Briefing: Cancer newsletter — what matters in cancer research, free to your inbox weekly.

Get what matters in cancer research, free to your inbox weekly. Sign up for Nature Briefing: Cancer