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Ido brings down the pressure in systemic inflammation

Nature Medicine volume 16, pages 265–267 (2010)Cite this article

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Systemic inflammation results in a life-threatening drop in blood pressure. Targeting known players of blood pressure regulation has so far failed to improve outcomes for individuals with sepsis. But a study points to a regulatory pathway involving the amino acid metabolite kynurenine that may provide new avenues for therapies (pages 279–285).

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Figure 1: Endothelial pathways regulating vascular smooth muscle tone.

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Authors and Affiliations

  1. Franz Hofmann is at Forschergruppe 923, Institut für Pharmakologie und Toxikologie, Technische Universität München, München, Germany.,

    Franz Hofmann

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  1. Franz Hofmann
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Correspondence to Franz Hofmann.

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The author declares no competing financial interests.

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Hofmann, F. Ido brings down the pressure in systemic inflammation. Nat Med 16, 265–267 (2010). https://doi.org/10.1038/nm0310-265

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