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A sweet target for innate immunity

Galectins are carbohydrate-binding proteins with diverse activities, but there is no unifying picture of their primary physiological role. Galectins now emerge as autonomous bacteria-killing agents (pages 295–301), unexpected findings that may point to a principal role of these proteins in innate immunity.

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Figure 1: Gal-4 and Gal-8 serve as bactericidal lectins.

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Correspondence to Fu-Tong Liu or Charles L Bevins.

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Liu, FT., Bevins, C. A sweet target for innate immunity. Nat Med 16, 263–264 (2010). https://doi.org/10.1038/nm0310-263

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