Three studies implicate Kindlin-3, a molecule that mediates signaling through integrins, in a rare disorder characterized by spontaneous bleeding and susceptibility to infection (pages 300–305, 306–312 and 313–318).
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 12 print issues and online access
$209.00 per year
only $17.42 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Anderson, D.C. & Springer, T.A. Annu. Rev. Med. 38, 175–194 (1987).
Alon, R. & Etzioni, A. Trends Immunol. 24, 561–566 (2003).
Bergmeier, W. et al. J. Clin. Invest. 117, 1699–1707 (2007).
Pasvolsky, R. et al. J. Exp. Med. 204, 1571–1582 (2007).
Svensson, L. et al. Nat. Med. 15, 306–312 (2009).
Malinin, N.L. et al. Nat. Med. 15, 313–318 (2009).
Moser, M. et al. Nat. Med. 15, 300–305 (2009).
Kindler, T. Br. J. Dermatol. 66, 104–111 (1954).
Montanez, E. et al. Genes Dev. 22, 1325–1330 (2008).
Moser, M., Nieswandt, B., Ussar, S., Pozgajova, M. & Fässler, R. Nat. Med. 14, 325–330 (2008).
Teitelbaum, S.L. Ann. NY Acad. Sci. 1068, 95–99 (2006).
Kuijpers, T.W. et al. Blood published online, doi:10.1182/blood-2008-10-182154 (8 December 2008).
Mory, A. et al. Blood 112, 2591 (2008).
Valor, L.M. & Grant, S.G. PLoS ONE 2, e1303 (2007).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Hidalgo, A., Frenette, P. When integrins fail to integrate. Nat Med 15, 249–250 (2009). https://doi.org/10.1038/nm0309-249
Issue Date:
DOI: https://doi.org/10.1038/nm0309-249