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A rendezvous before rejection: Where do T cells meet transplant antigens?

Nature Medicine volume 8, pages 220–222 (2002)Cite this article

Interactions between recipient T cells and donor endothelial graft cells may be an important mechanism for both acute and chronic rejection of vascularized allografts. This finding provides a starting point for investigations to develop novel ways of inducing long-lasting immunologic tolerance to donor antigens. (pages 233–239)

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Figure 1: Allorecognition pathways and graft rejection.

Bob Crimi

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  1. Brigham and Women's Hospital and Children's Hospital Harvard Medical School, Boston, Massachusetts, USA

    David M. Briscoe & Mohamed H. Sayegh

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  1. David M. Briscoe
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  2. Mohamed H. Sayegh
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Briscoe, D., Sayegh, M. A rendezvous before rejection: Where do T cells meet transplant antigens?. Nat Med 8, 220–222 (2002). https://doi.org/10.1038/nm0302-220

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