The receptor for interleukin-7 is a susceptibility factor in multiple sclerosis, but its exact role in the disease has been unclear. New findings outline a function for interleukin-7 in the biology of T helper 17 cells, a subset of T cells recently identified as key players in autoimmune disorders (pages 191–197).
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The authors declare no competing financial interests.
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Veldhoen, M., Seddon, B. Empowering T helper 17 cells in autoimmunity. Nat Med 16, 166–168 (2010). https://doi.org/10.1038/nm0210-166